About one in 10,000 babies in the U.S. is born with phenylketonuria, an inherited metabolic disorder. This in-depth program explores diagnostic methods, such as the Guthrie test, automated fluorometric analysis, and mass spectrometry. The biochemistry and metabolic pathways of PKU are closely examined. Dietary experts and patients, both adults and children, discuss treatment strategies as well as complications due to pregnancy. This valuable resource will be of particular interest to students of biochemistry and medicine. (29 minutes)

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